Potent hemithioindigo-based antimitotics photocontrol the microtubule cytoskeleton in cellulo

• Alexander Sailer,
• Franziska Ermer,
• Yvonne Kraus,
• Rebekkah Bingham,
• Ferdinand H. Lutter,
• Julia Ahlfeld and
• Oliver Thorn-Seshold

Beilstein J. Org. Chem. 2020, 16, 125–134, doi:10.3762/bjoc.16.14

• , and high-yielding synthesis of HITub-4. Chemical structures of HITubs. Key variations with respect to HITub-4 are highlighted in dashed boxes. Photocharacterisation of HITub-4. a) Photochemical and thermal isomerisation. b) UV–vis spectra after saturating illumination at λ = 450, 505, and 530 nm

Recent advances towards azobenzene-based light-driven real-time information-transmitting materials

• Jaume García-Amorós and
• Dolores Velasco

Beilstein J. Org. Chem. 2012, 8, 1003–1017, doi:10.3762/bjoc.8.113

• azophenols; thermal isomerisation; Introduction Nowadays, there is an ever growing interest in molecular switching materials because of the very rapid development of modern technology. This tendency arises from the great applicability of such systems as active data elaboration, storage and communication

• directly related with the thermal isomerisation rate of the photo-sensitive azo-dye in the dark, that is, with the relaxation time of the cis isomer of the azo-moiety. Slow thermally back-isomerising azoderivatives are valuable photoactive basic materials for information storage (memory) purposes. A

• photomagnetic actuating purposes [38]. In this review, we present the efforts made in our research group over the past few years regarding the molecular design of new photosensitive azoderivatives endowed with very fast cis-to-trans thermal isomerisation processes, with the main aim of transmitting optical